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Pfizer Stock Slips as Wall Street Stays Cautious Despite Updated Guidance
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Pfizer Stock Slips as Wall Street Stays Cautious Despite Updated Guidance

Dec 16, 2025
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Pfizer Stock Slips: Pfizer Inc. (NYSE: PFE) was in focus on Tuesday after receiving updated analyst coverage from Bank of America Securities. Despite revised financial guidance from the company, Wall Street sentiment remained largely cautious.

Five-star Bank of America Securities analyst Jason Gerberry reaffirmed a Hold rating on Pfizer stock, maintaining a $28 price target. The target implies a potential 5.9% upside, closely aligning with a similar outlook issued last week by Morgan Stanley analyst Terence Flynn, who also holds a neutral stance on the shares.

Analysts See Limited Growth Catalysts

Gerberry’s assessment followed Pfizer’s newly released financial guidance, which initially gave the stock a modest lift. However, the analyst was unconvinced by the update, citing a lack of near-term growth catalysts and structural challenges expected to weigh on the company through 2029.

According to the report, Pfizer’s outlook relies heavily on strict cost controls rather than innovation-driven expansion. Gerberry projects flat earnings growth, declining revenue, and minimal new product launches or pipeline announcements over the next year—factors that continue to cap upside potential.

Pfizer Stock Performance Today

Pfizer shares rose nearly 1% in pre-market trading Tuesday, following a 2.24% gain on Monday. The stock is up 6.83% year-to-date, though performance over the past 12 months has remained largely flat.

Trading volume was relatively muted, with roughly 1 million shares changing hands early Tuesday, well below the company’s three-month average daily volume of 73 million shares.

Wall Street Consensus: Hold

Overall, Wall Street maintains a Hold consensus on Pfizer stock. Over the past three months, analysts have issued five Buy, 11 Hold, and one Sell ratings. The average price target stands at $28.44, suggesting a potential 7.6% upside from current levels.

While Pfizer remains a stable pharmaceutical heavyweight, analysts suggest investors may need to wait for clearer pipeline progress or strategic catalysts before meaningful upside emerges.

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